{"id":4953,"date":"2022-11-29T10:54:45","date_gmt":"2022-11-29T01:54:45","guid":{"rendered":"https:\/\/cureverse.co.kr\/en\/?post_type=record&#038;p=4953"},"modified":"2025-05-13T12:04:07","modified_gmt":"2025-05-13T03:04:07","slug":"kist-%ec%b6%9c%ec%9e%90-%ed%81%90%ec%96%b4%eb%b2%84%ec%8a%a4-%eb%87%8c%ec%a7%88%ed%99%98-%ec%b9%98%eb%a3%8c%ec%a0%9c-%ea%b0%9c%eb%b0%9c","status":"publish","type":"record","link":"https:\/\/cureverse.co.kr\/en\/record\/kist-%ec%b6%9c%ec%9e%90-%ed%81%90%ec%96%b4%eb%b2%84%ec%8a%a4-%eb%87%8c%ec%a7%88%ed%99%98-%ec%b9%98%eb%a3%8c%ec%a0%9c-%ea%b0%9c%eb%b0%9c\/","title":{"rendered":"KIST \ucd9c\uc790&#8217; \ud050\uc5b4\ubc84\uc2a4, \ub1cc\uc9c8\ud658 \uce58\ub8cc\uc81c \uac1c\ubc1c"},"content":{"rendered":"<p>\ud55c\uad6d\uacfc\ud559\uae30\uc220\uc5f0\uad6c\uc6d0(KIST) \ucd9c\uc790\uae30\uc5c5 \ud050\uc5b4\ubc84\uc2a4\uac00 &#8216;\ud6a8\ub2a5&#8217;\uacfc &#8216;\uc57d\ubb3c\uc131&#8217;\uc744 \uacb8\ube44\ud55c \uc2e0\uc57d \ud6c4\ubcf4 \ubb3c\uc9c8\uc744 \uac1c\ubc1c\ud588\ub2e4. \ud6c4\ubcf4 \ubb3c\uc9c8\uc774 \uc544\uc9c1 \ube44\uc784\uc0c1 \ub2e8\uacc4\uc9c0\ub9cc \ud0c1\uc6d4\ud568\uc744 \uc778\uc815\ubc1b\uc558\ub2e4. \ud050\uc5b4\ubc84\uc2a4\ub294 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc774\ub098 \ub2e4\ubc1c\uc131 \uacbd\ud654\uc99d \ub4f1 \ub09c\uce58\uc131 \ub1cc\u00b7\uc2e0\uacbd\uc9c8\ud658 \uce58\ub8cc\uc81c \uac1c\ubc1c\uc5d0 \ub098\uc11c\uace0 \uc788\ub2e4\uace0 29\uc77c \ubc1d\ud614\ub2e4.<\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-4956\" src=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41.jpg\" alt=\"\" width=\"1000\" height=\"667\" srcset=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41.jpg 1000w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41-300x200.jpg 300w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41-768x512.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p>\uccab \ubc88\uc9f8 \ud30c\uc774\ud504\ub77c\uc778 \uc784\uc0c1 \ud6c4\ubcf4\uc778 &#8216;CV-01&#8217;\uc740 \uc54c\uce20\ud558\uc774\uba38\ubcd1\uc774\ub098 \ud30c\ud0a8\uc2a8\ubcd1\uacfc \uac19\uc740 \ub1cc \uc9c8\ud658 \uce58\ub8cc\ub97c \uc704\ud55c \uac83\uc774\ub2e4. \uc99d\uc0c1 \uc644\ud654 \uc218\uc900\uc778 \uae30\uc874 \uc57d\uacfc \ub2ec\ub9ac \uc2e4\uc81c \uce58\ub8cc \ud6a8\uacfc \ucc3d\ucd9c\uc774 \ubaa9\ud45c\ub2e4. CV-01\uc740 Keap1, Nrf2 \ub2e8\ubc31\uc9c8 \uac04 \uc0c1\ud638\uc791\uc6a9\uc744 \ub9c9\uc544 \ub1cc \uc9c8\ud658 \uce58\ub8cc \ud6a8\uacfc\ub97c \ubcf4\uc778\ub2e4. Nrf2 \ub2e8\ubc31\uc9c8\uc740 \uc138\ud3ec \ubc29\uc5b4\uae30\uc804 \uad00\ub828 \uc720\uc804\uc790 \ubc1c\ud604\uc744 \ub3d5\ub294\ub2e4.<\/p>\n<p>\ub1cc \uc9c8\ud658\uacfc\ub3c4 \uc5f0\uad00\uc774 \uae4a\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1 \ud658\uc790\ub294 Nrf2 \uae30\ub2a5\uc774 \ud604\uc800\ud788 \uc800\ud558\ub418\ub294 \uc608\uac00 \ub9ce\uc740\ub370 Keap1 \ub2e8\ubc31\uc9c8\uc740 \uc774\ub7f0 Nrf2\uc640 \uacb0\ud569\ud574\uc11c \uadf8 \uc5ed\ud560\uc744 \uc81c\ud55c\ud558\uace0 \uae30\ub2a5\uc744 \uc870\uc808\ud55c\ub2e4. CV-01\uc740 Keap1\uc758 \ud2b9\uc815 \uc544\ubbf8\ub178\uc0b0\uc744 \ubcc0\ud615\uc2dc\ucf1c Nrf2\uc640\uc758 \uc0c1\ud638\uc791\uc6a9\uc744 \ucc28\ub2e8\ud55c\ub2e4. \uc774\ub85c\uc368 Nrf2 \ud65c\uc131\ud654 \uc870\uc808\uc774 \uac00\ub2a5\ud574\uc9c4\ub2e4.<\/p>\n<p>\ud050\uc5b4\ubc84\uc2a4\ub294 CV-01\uc774 \uae30\uc874 \ub1cc \uc9c8\ud658 \uce58\ub8cc\uc81c\uc640 \ucc28\ubcc4\ud654\ud55c \ud6a8\ub2a5\uc744 \ubcf4\uc778\ub2e4\uace0 \uc124\uba85\ud588\ub2e4. \uad00\ub828 \ud6a8\ub2a5 \uac80\uc99d\uc5d0 \uc8fc\ub85c \uc4f0\uc774\ub294 &#8216;\ubaa8\ub9ac\uc2a4 \uc218\uc870\uc2e4\ud5d8&#8217; &#8216;\uc218\ub3d9\uc801 \ud68c\ud53c \uc2e4\ud5d8(PA \ud14c\uc2a4\ud2b8)&#8217; \ub4f1\uc5d0\uc11c CV-01\uc744 \uc4f4 \uce58\ub9e4 \uc950 \ubaa8\ub378\uc774 \uc815\uc0c1 \uc950\uc640 \uc720\uc0ac\ud55c \ud559\uc2b5\u00b7\uae30\uc5b5 \ub2a5\ub825\uc744 \ubcf4\uc600\ub2e4. \uc54c\uce20\ud558\uc774\uba38\ubcd1\uacfc \ud30c\ud0a8\uc2a8\ubcd1 \ubaa8\ub450 \uc720\uc758\ubbf8\ud55c \uacb0\uacfc\uac00 \ub098\uc654\ub2e4. \uc57d\ubb3c\uc131\ub3c4 \ub6f0\uc5b4\ub098\ub2e4. \uc57d\ubb3c\uc131\uc740 \uc57d \ud2b9\uc131 \ubc1c\ud718\uc5d0 \ud544\uc694\ud55c \uc885\ud569\uc801 \uc131\uc9c8\uc774\ub2e4. \ud761\uc218\u00b7\ubd84\ud3ec\u00b7\ub300\uc0ac\u00b7\ubc30\ucd9c\uc774 \uc798 \uc774\ub904\uc9c0\ub294\uc9c0\uc640 \ub3c5\uc131\uc740 \uc5c6\ub294\uc9c0 \ub4f1\uc774 \uadf8\uac83\uc774\ub2e4. CV-01\uc740 \uc774\ub97c \ub2e4\ub8e8\ub294 &#8216;ADME\/Tox&#8217; \ud3c9\uac00\uc5d0\uc11c \uc6b0\uc218\ud55c \uacb0\uacfc\ub97c \ubcf4\uc600\ub2e4.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-4955\" src=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_b.jpg\" alt=\"\" width=\"1000\" height=\"667\" srcset=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_b.jpg 1000w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_b-300x200.jpg 300w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_b-768x512.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p>\ub450 \ubc88\uc9f8 \ud30c\uc774\ud504\ub77c\uc778 &#8216;CV-02&#8217;\ub294 \uc790\uac00\uba74\uc5ed\uc9c8\ud658\uc778 \ub2e4\ubc1c\uc131 \uacbd\ud654\uc99d \uce58\ub8cc\uc81c \ud6c4\ubcf4\ubb3c\uc9c8\uc774\ub2e4. \uae30\uc874 \uce58\ub8cc\uc81c\uc640 \ub9c8\ucc2c\uac00\uc9c0\ub85c \ud608\uc561 \ub0b4 \uba74\uc5ed\uc138\ud3ec \uc774\ub3d9\uc744 \uc870\uc808\ud558\ub294 &#8216;S1P1&#8217; \ub2e8\ubc31\uc9c8\uc774 \uce58\ub8cc \ud0c0\uae43\uc774\ub2e4. \ubd80\uc791\uc6a9\uc744 \ud574\uacb0\ud588\ub2e4\ub294 \uc810\uc774 \ucc28\ubcc4\ud654\ub2e4. \uae30\uc874 \uce58\ub8cc\uc81c\ub294 \uc2ec\uc7a5\uc774 \ub290\ub9ac\uac8c \ub6f0\ub294 &#8216;\uc11c\ub9e5&#8217;\uc744 \uc720\ubc1c\ud560 \uc218 \uc788\ub2e4. CV-02\ub294 S1P1\uc758 \uad6c\uc870 \ubcc0\ud654\ub97c \uc77c\uc73c\ucf1c \ubd80\uc791\uc6a9\uacfc \uad00\ub828\ud55c \ub2e8\ubc31\uc9c8\uc758 \uc0c1\ud638\uc791\uc6a9\uc744 \ub9c9\ub294\ub2e4. \ubd80\uc791\uc6a9 \ub300\uc2e0 \uce58\ub8cc \uad00\ub828 \uc0c1\ud638\uc791\uc6a9\uc774 \ub298\uc5b4\ub098\uba74\uc11c \ud6a8\ub2a5 \uc5ed\uc2dc \ub369\ub2ec\uc544 \uc99d\ub300\ub41c\ub2e4. \ud050\uc5b4\ubc84\uc2a4\ub294 \uc0ac\ub78c \uc2ec\uc7a5 \uc870\uc9c1\uc744 \uc774\uc6a9\ud55c \ud14c\uc2a4\ud2b8 \uacb0\uacfc \ub2e4\uad6d\uc801 \ud68c\uc0ac\uc758 \uacbd\uc7c1 \uc57d\ubb3c \ub300\ube44 \ubd80\uc791\uc6a9 \uc548\uc804\uc131\uc774 100\ubd84\uc758 1 \uc218\uc900\uc784\uc744 \ud655\uc778\ud588\ub2e4\uace0 \ubc1d\ud614\ub2e4.<\/p>\n<p><img decoding=\"async\" class=\"aligncenter size-full wp-image-4954\" src=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_c.jpg\" alt=\"\" width=\"1000\" height=\"545\" srcset=\"https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_c.jpg 1000w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_c-300x164.jpg 300w, https:\/\/cureverse.co.kr\/en\/wp-content\/uploads\/2025\/05\/cv_41_c-768x419.jpg 768w\" sizes=\"(max-width: 1000px) 100vw, 1000px\" \/><\/p>\n<p>\uc870\uc131\uc9c4 \ud050\uc5b4\ubc84\uc2a4 \ub300\ud45c\ub294 \u201c\uc2e0\uc57d \uac1c\ubc1c\uc740 \ud30c\uc774\ud504\ub77c\uc778\uc774 \ud575\uc2ec\uc774\uace0 \uc62c\ubc14\ub978 \uad6c\uc870\uc758 \uc6b0\uc218\ud55c \ud30c\uc774\ud504\ub77c\uc778\uc774\ub77c\ub294 \ub370 \uac15\uc810\uc774 \uc788\ub2e4\u201d\uace0 \ub9d0\ud588\ub2e4. \uacf5\ub3d9\ucc3d\uc5c5\uc790\uc778 \ubc15\uae30\ub355 KIST \ub1cc\uc9c8\ud658\uadf9\ubcf5\uc5f0\uad6c\ub2e8\uc7a5\uacfc \uc9c4\uc815\uc6b1 \ucd5c\uace0\uc804\ub7b5\ucc45\uc784\uc790(CSO)\ub294 \u201c\uc55e\uc73c\ub85c\ub3c4 \uafb8\uc900\ud788 \uc6b0\uc218\ud55c \ud30c\uc774\ud504\ub77c\uc778\uacfc \uc57d\ubb3c\uc744 \uac1c\ubc1c, \uc131\uacfc\ub97c \uc774\uc5b4 \uac00\uaca0\ub2e4\u201d\uace0 \uc804\ud588\ub2e4.<\/p>\n<p>\uc131\uacfc \ucc3d\ucd9c\uc5d0\ub294 KIST\uc758 \uc9c0\uc6d0\uc774 \uc788\uc5c8\ub2e4. \ud050\uc5b4\ubc84\uc2a4\ub294 KIST\uc758 \ubc14\uc774\uc624 \uc2a4\ud0c0\ud2b8\uc5c5 \ucc3d\uc5c5 \uc9c0\uc6d0 \ud504\ub85c\uadf8\ub7a8\uc744 \uae30\ud68c\ub85c \ucc3d\uc5c5\ud588\ub2e4. \ud050\uc5b4\ubc84\uc2a4\ub294 \ucc3d\uc5c5 1\ub144 \ub9cc\uc5d0 81\uc5b5\uc6d0 \uc2dc\ub9ac\uc988A \ud22c\uc790\ub97c \ub04c\uc5b4\ub0c8\ub2e4. &#8216;2022 \uc5f0\uad6c\uac1c\ubc1c\ud2b9\uad6c \ud601\uc2e0\uae30\uc5c5 \ud1b5\ud569 IR \uacbd\uc9c4\ub300\ud68c&#8217;\uc5d0\uc11c \uae30\uc220\ub300\uc0c1(\uacfc\ud559\uae30\uc220\uc815\ubcf4\ud1b5\uc2e0\ubd80 \uc7a5\uad00\uc0c1)\uc744 \ubc1b\uae30\ub3c4 \ud588\ub2e4. \ud30c\uc774\ud504\ub77c\uc778 \ube44\uc784\uc0c1 \uacfc\uc815\uc744 \ub0b4\ub144 \ucd08\uc5d0 \ub9c8\uce58\uace0 2024\ub144\ubd80\ud130 \uc784\uc0c1\uc5d0 \ub4e4\uc5b4\uac00\uc11c \uc131\uacfc\ub97c \uc774\uc5b4 \uac04\ub2e4\ub294 \uacc4\ud68d\uc774\ub2e4.<\/p>\n<p>\uae40\uc601\uc900\uae30\uc790 kyj85@etnews.com<\/p>\n","protected":false},"featured_media":4961,"parent":0,"template":"","meta":{"_acf_changed":false},"record-category":[],"class_list":["post-4953","record","type-record","status-publish","has-post-thumbnail","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/record\/4953","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/record"}],"about":[{"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/types\/record"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/media\/4961"}],"wp:attachment":[{"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/media?parent=4953"}],"wp:term":[{"taxonomy":"record-category","embeddable":true,"href":"https:\/\/cureverse.co.kr\/en\/wp-json\/wp\/v2\/record-category?post=4953"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}